Recombinant Mycobacterium bovis BCG Expressing the Sm14 Antigen of Schistosoma mansoni Protects Mice from Cercarial Challenge

The Sm14 antigen of Schistosoma mansoni was cloned and expressed in Mycobacterium bovis BCG as a fusion with the Mycobacterium fortuitum β-lactamase protein under the control of its promoter, pBlaF*; the protein was localized in the bacterial cell wall. The rBCG-Sm14 strain was shown to be relativel...

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Main Authors: Varaldo, Paula B., Leite, Luciana C. C., Dias, Waldely O., Miyaji, Eliane N., Torres, Fabio I. G., Gebara, Vera C., Armôa, Geraldo R. G., Campos, Adriano S., Matos, Denise C. S., Winter, Nathalie, Gicquel, Brigitte, Vilar, Mônica M., McFadden, Johnjoe, Almeida, Marilia S., Tendler, Miriam, McIntosh, Douglas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Microbial Immunity and Vaccines
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC415698/
https://ncbi.nlm.nih.gov/pubmed/15155638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.6.3336-3343.2004
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