A Heptosyltransferase Mutant of Pasteurella multocida Produces a Truncated Lipopolysaccharide Structure and Is Attenuated in Virulence

Pasteurella multocida is the causative agent of fowl cholera in birds. In a previous study using signature-tagged mutagenesis, we identified a mutant, AL251, which was attenuated for virulence in mice and in the natural chicken host. Sequence analysis indicated that AL251 had an insertional inactiva...

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Hlavní autoři: Harper, Marina, Cox, Andrew D., St. Michael, Frank, Wilkie, Ian W., Boyce, John D., Adler, Ben
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Molecular Pathogenesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC415681/
https://ncbi.nlm.nih.gov/pubmed/15155650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.6.3436-3443.2004
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