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Structural insights into +1 frameshifting promoted by expanded or modification-deficient anticodon stem loops

Maintenance of the correct reading frame on the ribosome is essential for accurate protein synthesis. Here, we report structures of the 70S ribosome bound to frameshift suppressor tRNA(SufA6) and N1-methylguanosine at position 37 (m(1)G37) modification-deficient anticodon stem loop(Pro), both of whi...

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Autors principals: Maehigashi, Tatsuya, Dunkle, Jack A., Miles, Stacey J., Dunham, Christine M.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156745/
https://ncbi.nlm.nih.gov/pubmed/25128388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1409436111
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