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Tip-link protein protocadherin 15 interacts with transmembrane channel-like proteins TMC1 and TMC2

The tip link protein protocadherin 15 (PCDH15) is a central component of the mechanotransduction complex in auditory and vestibular hair cells. PCDH15 is hypothesized to relay external forces to the mechanically gated channel located near its cytoplasmic C terminus. How PCDH15 is coupled to the tran...

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Detalhes bibliográficos
Main Authors: Maeda, Reo, Kindt, Katie S., Mo, Weike, Morgan, Clive P., Erickson, Timothy, Zhao, Hongyu, Clemens-Grisham, Rachel, Barr-Gillespie, Peter G., Nicolson, Teresa
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156717/
https://ncbi.nlm.nih.gov/pubmed/25114259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1402152111
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