Reduction of the Peptidoglycan Crosslinking Causes a Decrease in Stiffness of the Staphylococcus aureus Cell Envelope

We have used atomic-force microscopy (AFM) to probe the effect of peptidoglycan crosslinking reduction on the elasticity of the Staphylococcus aureus cell wall, which is of particular interest as a target for antimicrobial chemotherapy. Penicillin-binding protein 4 (PBP4) is a nonessential transpept...

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Detalhes bibliográficos
Main Authors: Loskill, Peter, Pereira, Pedro M., Jung, Philipp, Bischoff, Markus, Herrmann, Mathias, Pinho, Mariana G., Jacobs, Karin
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2014
Assuntos:
Cell Biophysics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156677/
https://ncbi.nlm.nih.gov/pubmed/25185544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.07.029
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