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IL-12 is required for mTOR regulation of memory CTLs during viral infection
The induction of functional memory CTLs is a major goal of vaccination against intracellular pathogens. IL-12 is critical for the generation of memory CTLs, and inhibition of mTOR by rapamycin can effectively enhance the memory CTL response. Yet, the role of IL-12 in mTOR’s regulation of memory CTL...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4156562/ https://ncbi.nlm.nih.gov/pubmed/24898389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gene.2014.33 |
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