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Using PBPK guided “Body-on-a-Chip” Systems to Predict Mammalian Response to Drug and Chemical Exposure

The continued development of in vitro systems that accurately emulate human response to drugs or chemical agents will impact drug development, our understanding of chemical toxicity, and enhance our ability to respond to threats from chemical or biological agents. A promising technology is to build...

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Hlavní autoři: Sung, Jong Hwan, Srinivasan, Balaji, Esch, Mandy Brigitte, McLamb, William T., Bernabini, Catia, Shuler, Michael L., Hickman, James J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156540/
https://ncbi.nlm.nih.gov/pubmed/24951471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370214529397
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