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A strategy for integrating essential 3D microphysiological systems of human organs for realistic anti-cancer drug screening

Cancer is one of the leading causes of morbidity and mortality around the world. Despite some success, traditional anti-cancer drugs developed to reduce tumor growth face important limitations primarily due to undesirable bone marrow and cardiovascular toxicity. Many drugs showing promise in preclin...

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Detalhes bibliográficos
Main Authors: Heylman, Christopher, Sobrino, Agua, Shirure, Venktesh S., Hughes, Christopher C.W., George, Steven C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156538/
https://ncbi.nlm.nih.gov/pubmed/24740872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370214525295
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