The Genetics of Mexico Recapitulates Native American Substructure and Affects Biomedical Traits

Mexico harbors great cultural and ethnic diversity, yet fine-scale patterns of human genome-wide variation from this region remain largely uncharacterized. We studied genomic variation within Mexico from over 1,000 individuals representing 20 indigenous and 11 mestizo populations. We found striking...

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Main Authors: Moreno-Estrada, Andrés, Gignoux, Christopher R., Fernández-López, Juan Carlos, Zakharia, Fouad, Sikora, Martin, Contreras, Alejandra V., Acuña-Alonzo, Victor, Sandoval, Karla, Eng, Celeste, Romero-Hidalgo, Sandra, Ortiz-Tello, Patricia, Robles, Victoria, Kenny, Eimear E., Nuño-Arana, Ismael, Barquera-Lozano, Rodrigo, Macín-Pérez, Gastón, Granados-Arriola, Julio, Huntsman, Scott, Galanter, Joshua M., Via, Marc, Ford, Jean G., Chapela, Rocío, Rodriguez-Cintron, William, Rodríguez-Santana, Jose R., Romieu, Isabelle, Sienra-Monge, Juan José, Navarro, Blanca del Rio, London, Stephanie J., Ruiz-Linares, Andrés, Garcia-Herrera, Rodrigo, Estrada, Karol, Hidalgo-Miranda, Alfredo, Jimenez-Sanchez, Gerardo, Carnevale, Alessandra, Soberón, Xavier, Canizales-Quinteros, Samuel, Rangel-Villalobos, Héctor, Silva-Zolezzi, Irma, Burchard, Esteban Gonzalez, Bustamante, Carlos D.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156478/
https://ncbi.nlm.nih.gov/pubmed/24926019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1251688
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