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Adverse Drug Reaction Prediction Using Scores Produced by Large-Scale Drug-Protein Target Docking on High-Performance Computing Machines

Late-stage or post-market identification of adverse drug reactions (ADRs) is a significant public health issue and a source of major economic liability for drug development. Thus, reliable in silico screening of drug candidates for possible ADRs would be advantageous. In this work, we introduce a co...

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Autori principali: LaBute, Montiago X., Zhang, Xiaohua, Lenderman, Jason, Bennion, Brian J., Wong, Sergio E., Lightstone, Felice C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156361/
https://ncbi.nlm.nih.gov/pubmed/25191698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106298
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