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Acidification Asymmetrically Affects Voltage-dependent Anion Channel Implicating the Involvement of Salt Bridges

The voltage-dependent anion channel (VDAC) is the major pathway for ATP, ADP, and other respiratory substrates through the mitochondrial outer membrane, constituting a crucial point of mitochondrial metabolism regulation. VDAC is characterized by its ability to “gate” between an open and several “cl...

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Autori principali: Teijido, Oscar, Rappaport, Shay M., Chamberlin, Adam, Noskov, Sergei Y., Aguilella, Vicente M., Rostovtseva, Tatiana K., Bezrukov, Sergey M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156087/
https://ncbi.nlm.nih.gov/pubmed/24962576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.576314
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