Fitness Cost of SCCmec and Methicillin Resistance Levels in Staphylococcus aureus

Transformation of a type I SCCmec element into Staphylococcus aureus yielded highly oxacillin-resistant transformants with a reduced growth rate. Faster-growing variants could again be selected at the cost of reduced resistance levels, demonstrating an inverse correlation between oxacillin resistanc...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Ender, Miriam, McCallum, Nadine, Adhikari, Rajan, Berger-Bächi, Brigitte
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2004
Subjects:
Mechanisms of Resistance
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC415608/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15155238/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AAC.48.6.2295-2297.2004
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