The Combined Structural and Kinetic Characterization of a Bacterial Nitronate Monooxygenase from Pseudomonas aeruginosa PAO1 Establishes NMO Class I and II

Nitronate monooxygenase (NMO) oxidizes the mitochondrial toxin propionate 3-nitronate (P3N) to malonate semialdehyde. The enzyme has been previously characterized biochemically in fungi, but no structural information is available. Based on amino acid similarity 4,985 genes are annotated in the GenBa...

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Detalhes bibliográficos
Main Authors: Salvi, Francesca, Agniswamy, Johnson, Yuan, Hongling, Vercammen, Ken, Pelicaen, Rudy, Cornelis, Pierre, Spain, Jim C., Weber, Irene T., Gadda, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Enzymology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156069/
https://ncbi.nlm.nih.gov/pubmed/25002579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.577791
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