Insulin Protects Pancreatic Acinar Cells from Palmitoleic Acid-induced Cellular Injury

Acute pancreatitis is a serious and sometimes fatal inflammatory disease where the pancreas digests itself. The non-oxidative ethanol metabolites palmitoleic acid (POA) and POA-ethylester (POAEE) are reported to induce pancreatitis caused by impaired mitochondrial metabolism, cytosolic Ca(2+) ([Ca(2...

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Detalhes bibliográficos
Main Authors: Samad, Aysha, James, Andrew, Wong, James, Mankad, Parini, Whitehouse, John, Patel, Waseema, Alves-Simoes, Marta, Siriwardena, Ajith K., Bruce, Jason I. E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156068/
https://ncbi.nlm.nih.gov/pubmed/24993827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.589440
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