The p38β Mitogen-activated Protein Kinase Possesses an Intrinsic Autophosphorylation Activity, Generated by a Short Region Composed of the α-G Helix and MAPK Insert

Protein kinases are regulated by a large number of mechanisms that vary from one kinase to another. However, a fundamental activation mechanism shared by all protein kinases is phosphorylation of a conserved activation loop threonine residue. This is achieved in many cases via autophosphorylation. T...

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Détails bibliographiques
Auteurs principaux: Beenstock, Jonah, Ben-Yehuda, Sheer, Melamed, Dganit, Admon, Arie, Livnah, Oded, Ahn, Natalie G., Engelberg, David
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2014
Sujets:
Enzymology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156038/
https://ncbi.nlm.nih.gov/pubmed/25006254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.578237
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