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Direct Site-Specific Radiolabeling of an Affibody Protein with 4-[(18)F]Fluorobenzaldehyde via Oxime Chemistry
PURPOSE: In this study, we introduce a methodology for preparing (18)F-labeled Affibody protein, specifically (18)F-Anti-HER2 dimeric Affibody (14 kDa), for in vivo imaging of HER2neu with positron emission tomography (PET). PROCEDURES: We have used 4-[(18)F]fluorobenzaldehyde as a synthon to prepar...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4155982/ https://ncbi.nlm.nih.gov/pubmed/18481153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-008-0142-7 |
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