α-Galactosylceramide and Novel Synthetic Glycolipids Directly Induce the Innate Host Defense Pathway and Have Direct Activity against Hepatitis B and C Viruses

α-Galactosylceramide is a glycolipid derived from marine sponges that is currently in human clinical trials as an anticancer agent. It has also been shown to be effective in reducing the amount of hepatitis B virus (HBV) DNA detected in mice that produce HBV constitutively from a transgene. It was a...

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Detalhes bibliográficos
Main Authors: Mehta, Anand S., Gu, Baohua, Conyers, Bertha, Ouzounov, Serguey, Wang, Lijuan, Moriarty, Robert M., Dwek, Raymond A., Block, Timothy M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC415597/
https://ncbi.nlm.nih.gov/pubmed/15155204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.6.2085-2090.2004
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