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Cancer CARtography: Charting out a new approach to cancer immunotherapy

Recently, chimeric antigen receptor (CAR) T-cell immunotherapy has entered clinical trials in patients with relapsed or refractory B-ALL. 19–28z CAR T-cells express a fusion protein comprised of an anti-CD19 mAb fused with CD28 costimulatory and CD3-zeta chain signaling domains. The current paper de...

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Detalhes bibliográficos
Main Authors: Patel, Jaina M., Dale, Gordon A., Vartabedian, Vincent F., Dey, Paulami, Selvaraj, Periasamy
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155747/
https://ncbi.nlm.nih.gov/pubmed/25186600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/imt.14.44
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