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Biochemical and Structural Insights into Microtubule Perturbation by CopN from Chlamydia pneumoniae

Although the actin network is commonly hijacked by pathogens, there are few reports of parasites targeting microtubules. The proposed member of the LcrE protein family from some Chlamydia species (e.g. pCopN from C. pneumoniae) binds tubulin and inhibits microtubule assembly in vitro. From the pCopN...

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Autori principali: Nawrotek, Agata, Guimarães, Beatriz G., Velours, Christophe, Subtil, Agathe, Knossow, Marcel, Gigant, Benoît
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155683/
https://ncbi.nlm.nih.gov/pubmed/25056950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.568436
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