MicroRNA-21 Promotes Glioblastoma Tumorigenesis by Down-regulating Insulin-like Growth Factor-binding Protein-3 (IGFBP3)

Despite advances in surgery, imaging, chemotherapy, and radiation, patients with glioblastoma multiforme (GBM), the most common histological subtype of glioma, have an especially dismal prognosis; >70% of GBM patients die within 2 years of diagnosis. In many human cancers, the microRNA miR-21 is...

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Detalhes bibliográficos
Main Authors: Yang, Chuan He, Yue, Junming, Pfeffer, Susan R., Fan, Meiyun, Paulus, Elena, Hosni-Ahmed, Amira, Sims, Michelle, Qayyum, Sohail, Davidoff, Andrew M., Handorf, Charles R., Pfeffer, Lawrence M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155674/
https://ncbi.nlm.nih.gov/pubmed/25059666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.593863
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