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Inactivation of the Mycobacterium tuberculosis Antigen 85 Complex by Covalent, Allosteric Inhibitors

The rise of multidrug-resistant and totally drug-resistant tuberculosis and the association with an increasing number of HIV-positive patients developing tuberculosis emphasize the necessity to find new antitubercular targets and drugs. The antigen 85 (Ag85) complex from Mycobacterium tuberculosis p...

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Bibliografske podrobnosti
Main Authors: Favrot, Lorenza, Lajiness, Daniel H., Ronning, Donald R.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155670/
https://ncbi.nlm.nih.gov/pubmed/25028518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.582445
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