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P300-dependent STAT3 acetylation is necessary for angiotensin II-induced pro-fibrotic responses in renal tubular epithelial cells

AIM: To explore the signal transducer and activator of transcription 3 (STAT3) signaling pathway, especially STAT3 acetylation, in angiotensin II (Ang II)-induced pro-fibrotic responses in renal tubular epithelial cells. METHODS: Rat renal tubular epithelial cell line (NRK-52E) was used. STAT3 acety...

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Detalhes bibliográficos
Main Authors: Ni, Jun, Shen, Yang, Wang, Zhen, Shao, De-cui, Liu, Jia, Kong, Ya-li, Fu, Lan-jun, Zhou, Li, Xue, Hong, Huang, Yu, Zhang, Wei, Yu, Chen, Lu, Li-min
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155527/
https://ncbi.nlm.nih.gov/pubmed/25088002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2014.54
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