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An atomic model of brome mosaic virus using direct electron detection and real-space optimization
Advances in electron cryo-microscopy have enabled structure determination of macromolecules at near-atomic resolution. However, structure determination, even using de novo methods, remains susceptible to model bias and overfitting. Here we describe a complete workflow for data acquisition, image pro...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Pub. Group
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4155512/ https://ncbi.nlm.nih.gov/pubmed/25185801 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5808 |
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