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Influence of target gene mutations on survival, stage and histology in sporadic microsatellite unstable colon cancers
High-frequency microsatellite unstable (MSI-H) colon tumors develop as a consequence of mutations at repetitive sequences in target genes. TGFBR2 and ACVR2, encoding TGFb superfamily receptors, and the proapoptotic gene BAX are frequent targets for frameshift mutation. We analyzed the effect of thes...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4155491/ https://ncbi.nlm.nih.gov/pubmed/16380996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.21710 |
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