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Hyperthermia Inhibits Recombination Repair of Gemcitabine-Stalled Replication Forks
BACKGROUND: Gemcitabine is a potent nucleoside analogue against solid tumors, but development of drug resistance is a substantial problem. Removal of gemcitabine incorporated into DNA by repair mechanisms may contribute to resistance in chemo-refractory solid tumors. Human hepatocellular carcinoma (...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4155430/ https://ncbi.nlm.nih.gov/pubmed/25128695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/dju183 |
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