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Microbicidal mechanisms of human granulocytes: synergistic effects of granulocyte elastase and myeloperoxidase or chymotrypsin-like cationic protein.

The antibacterial activity of a myeloperoxidase (MPO)-glucose oxidase system was found to be greatly increased by granulocyte elastase, present in azurophil granules of human neutrophils. The MPO-H2O3-mediated killing of both Escherichia coli and Staphylococcus aureus was potentiated by granuocyte e...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Odeberg, /, Olsson, I
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1976
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC415527/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12111/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.14.6.1276-1283.1976
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