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PePr: a peak-calling prioritization pipeline to identify consistent or differential peaks from replicated ChIP-Seq data

Motivation: ChIP-Seq is the standard method to identify genome-wide DNA-binding sites for transcription factors (TFs) and histone modifications. There is a growing need to analyze experiments with biological replicates, especially for epigenomic experiments where variation among biological samples c...

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Bibliographic Details
Main Authors: Zhang, Yanxiao, Lin, Yu-Hsuan, Johnson, Timothy D., Rozek, Laura S., Sartor, Maureen A.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155259/
https://ncbi.nlm.nih.gov/pubmed/24894502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu372
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