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GT-Scan: identifying unique genomic targets

Summary: A number of technologies, including CRISPR/Cas, transcription activator-like effector nucleases and zinc-finger nucleases, allow the user to target a chosen locus for genome editing or regulatory interference. Specificity, however, is a major problem, and the targeted locus must be chosen w...

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Detalhes bibliográficos
Main Authors: O’Brien, Aidan, Bailey, Timothy L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155256/
https://ncbi.nlm.nih.gov/pubmed/24860161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btu354
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