Clostridium difficile has a single sortase, SrtB, that can be inhibited by small-molecule inhibitors

BACKGROUND: Bacterial sortases are transpeptidases that covalently anchor surface proteins to the peptidoglycan of the Gram-positive cell wall. Sortase protein anchoring is mediated by a conserved cell wall sorting signal on the anchored protein, comprising of a C-terminal recognition sequence conta...

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Main Authors: Donahue, Elizabeth H, Dawson, Lisa F, Valiente, Esmeralda, Firth-Clark, Stuart, Major, Meriel R, Littler, Eddy, Perrior, Trevor R, Wren, Brendan W
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4155245/
https://ncbi.nlm.nih.gov/pubmed/25183427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12866-014-0219-1
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