Risk-associations between HLA-DPB1 T cell epitope matching and outcome of unrelated hematopoietic cell transplantation are independent from HLA-DPA1

HLA-DP antigens are beta-alpha heterodimers encoded by polymorphic HLA-DPB1 and -DPA1 alleles, respectively, in strong linkage disequilibrium (LD) with each other. Non-permissive unrelated donor (UD)-recipient HLA-DPB1 mismatches across three different T cell epitope (TCE) groups are associated with...

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Main Authors: Fleischhauer, Katharina, Fernandez-Viña, Marcelo A., Wang, Tao, Haagenson, Michael, Battiwalla, Minoo, Baxter-Lowe, Lee Ann, Ciceri, Fabio, Dehn, Jason, Gajewski, James, Hale, Gregory A., Heemskerk, Martin BA, Marino, Susana R., McCarthy, Philip L., Miklos, David, Oudshoorn, Machteld, Pollack, Marilyn S., Reddy, Vijay, Senitzer, David, Shaw, Bronwen E., Waller, Edmund K., Lee, Stephanie J., Spellman, Stephen R.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154997/
https://ncbi.nlm.nih.gov/pubmed/24955785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bmt.2014.122
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