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A functional variant in NKX3.1 associated with prostate cancer risk in the Selenium and Vitamin E Cancer Prevention Trial (SELECT)

NKX3.1 is an androgen-regulated prostate tumor suppressor protein. We previously found that antioxidant administration (N-acetylcysteine) in the Nkx3.1 knock-out mouse model promoted prostate epithelial proliferation, suggesting that NKX3.1 activity modifies the effect of antioxidant administration...

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Detalhes bibliográficos
Main Authors: Martinez, Erin E., Darke, Amy K., Tangen, Catherine M., Goodman, Phyllis J., Fowke, Jay H., Klein, Eric A., Abdulkadir, Sarki A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154984/
https://ncbi.nlm.nih.gov/pubmed/24894197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-14-0075
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