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Mechanical offloading of incisional wounds is associated with transcriptional downregulation of inflammatory pathways in a large animal model

Cutaneous scarring is a major source of morbidity and current therapies to mitigate scar formation remain ineffective. Although wound fibrosis and inflammation are highly linked, only recently have mechanical forces been implicated in these pathways. Our group has developed a topical polymer device...

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Detalhes bibliográficos
Main Authors: Januszyk, Michael, Wong, Victor W, Bhatt, Kirit A, Vial, Ivan N, Paterno, Josemaria, Longaker, Michael T, Gurtner, Geoffrey C
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154952/
https://ncbi.nlm.nih.gov/pubmed/24739276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/org.28818
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