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Pharmacodynamic effects of ivabradine, a negative chronotropic agent, in healthy cats

OBJECTIVE: To determine the pharmacodynamic effects of oral ivabradine in cats. ANIMALS: Eight healthy, adult domestic short hair cats. METHODS: Each cat underwent four study periods of 24 h, receiving either one dose of placebo or ivabradine (0.1 mg/kg, 0.3 mg/kg, and 0.5 mg/kg) in a single-blind r...

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Detalhes bibliográficos
Main Authors: Cober, Richard E., Schober, Karsten E., Buffington, Tony C.A., Li, Xiaobai, Riesen, Sabine C., Bonagura, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154821/
https://ncbi.nlm.nih.gov/pubmed/22030291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jvc.2011.06.001
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