Synergistic Anti-Inflammatory Activity of the Antimicrobial Peptides Human Beta-Defensin-3 (hBD-3) and Cathelicidin (LL-37) in a Three-Dimensional Co-Culture Model of Gingival Epithelial Cells and Fibroblasts

Given the spread of antibiotic resistance in bacterial pathogens, antimicrobial peptides that can also modulate the immune response may be a novel approach for effectively controlling periodontal infections. In the present study, we used a three-dimensional (3D) co-culture model of gingival epitheli...

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Detalhes bibliográficos
Main Authors: Bedran, Telma Blanca Lombardo, Mayer, Márcia Pinto Alves, Spolidorio, Denise Palomari, Grenier, Daniel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154759/
https://ncbi.nlm.nih.gov/pubmed/25187958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106766
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