Incorporation of glutamine repeats makes protein oligomerize: implications for neurodegenerative diseases.
Many transcription factors and some other proteins contain glutamine repeats; their abnormal expansion has been linked to several dominantly inherited neuro-degenerative diseases. Having found that poly(L-glutamine) alone forms beta-strands held together by hydrogen bonds between their amide groups,...
Na minha lista:
| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1995
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41547/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7604023/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.14.6509 |
| Tags: |
Sem tags, seja o primeiro a adicionar uma tag!
|