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Overexpression of the Novel MATE Fluoroquinolone Efflux Pump FepA in Listeria monocytogenes Is Driven by Inactivation of Its Local Repressor FepR

Whereas fluoroquinolone resistance mainly results from target modifications in gram-positive bacteria, it is primarily due to active efflux in Listeria monocytogenes. The aim of this study was to dissect a novel molecular mechanism of fluoroquinolone resistance in this important human pathogen. Isog...

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Detalhes bibliográficos
Main Authors: Guérin, François, Galimand, Marc, Tuambilangana, Fabrice, Courvalin, Patrice, Cattoir, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154695/
https://ncbi.nlm.nih.gov/pubmed/25188450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106340
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