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A Semi-Dominant Mutation in the General Splicing Factor SF3a66 Causes Anterior-Posterior Axis Reversal in One-Cell Stage C. elegans Embryos

Establishment of anterior-posterior polarity in one-cell stage Caenorhabditis elegans embryos depends in part on astral microtubules. As the zygote enters mitosis, these microtubules promote the establishment of a posterior pole by binding to and protecting a cytoplasmic pool of the posterior polari...

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Detalhes bibliográficos
Main Authors: Keikhaee, Mohammad R., Nash, Eric B., O'Rourke, Sean M., Bowerman, Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154684/
https://ncbi.nlm.nih.gov/pubmed/25188372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106484
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