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Genome-Wide Association Meta-analysis of Neuropathologic Features of Alzheimer's Disease and Related Dementias

Alzheimer's disease (AD) and related dementias are a major public health challenge and present a therapeutic imperative for which we need additional insight into molecular pathogenesis. We performed a genome-wide association study and analysis of known genetic risk loci for AD dementia using ne...

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Hlavní autoři: Beecham, Gary W., Hamilton, Kara, Naj, Adam C., Martin, Eden R., Huentelman, Matt, Myers, Amanda J., Corneveaux, Jason J., Hardy, John, Vonsattel, Jean-Paul, Younkin, Steven G., Bennett, David A., De Jager, Philip L., Larson, Eric B., Crane, Paul K., Kamboh, M. Ilyas, Kofler, Julia K., Mash, Deborah C., Duque, Linda, Gilbert, John R., Gwirtsman, Harry, Buxbaum, Joseph D., Kramer, Patricia, Dickson, Dennis W., Farrer, Lindsay A., Frosch, Matthew P., Ghetti, Bernardino, Haines, Jonathan L., Hyman, Bradley T., Kukull, Walter A., Mayeux, Richard P., Pericak-Vance, Margaret A., Schneider, Julie A., Trojanowski, John Q., Reiman, Eric M., Schellenberg, Gerard D., Montine, Thomas J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154667/
https://ncbi.nlm.nih.gov/pubmed/25188341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004606
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