Pre-miR-146a (rs2910164 G>C) Single Nucleotide Polymorphism Is Genetically and Functionally Associated with Leprosy

Mycobacterium leprae infects macrophages and Schwann cells inducing a gene expression program to facilitate its replication and progression to disease. MicroRNAs (miRNAs) are key regulators of gene expression and could be involved during the infection. To address the genetic influence of miRNAs in l...

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Hauptverfasser: Cezar-de-Mello, Paula F. T., Toledo-Pinto, Thiago G., Marques, Carolinne S., Arnez, Lucia E. A., Cardoso, Cynthia C., Guerreiro, Luana T. A., Antunes, Sérgio L. G., Jardim, Márcia M., Covas, Claudia de J. F., Illaramendi, Ximena, Dias-Baptista, Ida M., Rosa, Patrícia S., Durães, Sandra M. B., Pacheco, Antonio G., Ribeiro-Alves, Marcelo, Sarno, Euzenir N., Moraes, Milton O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154665/
https://ncbi.nlm.nih.gov/pubmed/25187983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0003099
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