Pep2Path: Automated Mass Spectrometry-Guided Genome Mining of Peptidic Natural Products

Nonribosomally and ribosomally synthesized bioactive peptides constitute a source of molecules of great biomedical importance, including antibiotics such as penicillin, immunosuppressants such as cyclosporine, and cytostatics such as bleomycin. Recently, an innovative mass-spectrometry-based strateg...

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Autors principals: Medema, Marnix H., Paalvast, Yared, Nguyen, Don D., Melnik, Alexey, Dorrestein, Pieter C., Takano, Eriko, Breitling, Rainer
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154637/
https://ncbi.nlm.nih.gov/pubmed/25188327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003822
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