Enhanced expression of codon optimized Mycobacterium avium subsp. paratuberculosis antigens in Lactobacillus salivarius

It is well documented that open reading frames containing high GC content show poor expression in A+T rich hosts. Specifically, G+C-rich codon usage is a limiting factor in heterologous expression of Mycobacterium avium subsp. paratuberculosis (MAP) proteins using Lactobacillus salivarius. However,...

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Autors principals: Johnston, Christopher D., Bannantine, John P., Govender, Rodney, Endersen, Lorraine, Pletzer, Daniel, Weingart, Helge, Coffey, Aidan, O'Mahony, Jim, Sleator, Roy D.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2014
Matèries:
Microbiology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154528/
https://ncbi.nlm.nih.gov/pubmed/25237653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2014.00120
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