Activated FoxM1 Attenuates Streptozotocin-Mediated β-Cell Death

The forkhead box transcription factor FoxM1, a positive regulator of the cell cycle, is required for β-cell mass expansion postnatally, during pregnancy, and after partial pancreatectomy. Up-regulation of full-length FoxM1, however, is unable to stimulate increases in β-cell mass in unstressed mice...

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Autori principali: Golson, Maria L., Maulis, Matthew F., Dunn, Jennifer C., Poffenberger, Greg, Schug, Jonathan, Kaestner, Klaus H., Gannon, Maureen A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2014
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Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154244/
https://ncbi.nlm.nih.gov/pubmed/25073103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2014-1024
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