A positive feedback loop between RIP3 and JNK controls non-alcoholic steatohepatitis

Non-alcoholic fatty liver disease (NAFLD) represents the most common liver disease in Western countries and often progresses to non-alcoholic steatohepatitis (NASH) leading ultimately to liver fibrosis and liver cancer. The occurrence of hepatocyte cell death—so far characterized as hepatocyte apopt...

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Detalhes bibliográficos
Main Authors: Gautheron, Jérémie, Vucur, Mihael, Reisinger, Florian, Cardenas, David Vargas, Roderburg, Christoph, Koppe, Christiane, Kreggenwinkel, Karina, Schneider, Anne Theres, Bartneck, Matthias, Neumann, Ulf Peter, Canbay, Ali, Reeves, Helen Louise, Luedde, Mark, Tacke, Frank, Trautwein, Christian, Heikenwalder, Mathias, Luedde, Tom
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154133/
https://ncbi.nlm.nih.gov/pubmed/24963148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201403856
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