Denosumab for Treatment of Hypercalcemia of Malignancy

CONTEXT: Hypercalcemia of malignancy (HCM) in patients with advanced cancer is often caused by excessive osteoclast-mediated bone resorption. Patients may not respond to or may relapse after iv bisphosphonate therapy. OBJECTIVE: We investigated whether denosumab, a potent inhibitor of osteoclast-med...

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Main Authors: Hu, Mimi I., Glezerman, Ilya G., Leboulleux, Sophie, Insogna, Karl, Gucalp, Rasim, Misiorowski, Waldemar, Yu, Bennett, Zorsky, Paul, Tosi, Diego, Bessudo, Alberto, Jaccard, Arnaud, Tonini, Giuseppe, Ying, Wendy, Braun, Ada, Jain, Rajul K.
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2014
Teme:
Endocrine Care
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154084/
https://ncbi.nlm.nih.gov/pubmed/24915117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2014-1001
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