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Effects of Low-Dose Estrogen Replacement During Childhood on Pubertal Development and Gonadotropin Concentrations in Patients With Turner Syndrome: Results of a Randomized, Double-Blind, Placebo-Controlled Clinical Trial

CONTEXT: The optimal approach to estrogen replacement in girls with Turner syndrome has not been determined. OBJECTIVE: The aim of the study was to assess the effects of an individualized regimen of low-dose ethinyl estradiol (EE2) during childhood from as early as age 5, followed by a pubertal indu...

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Main Authors: Quigley, Charmian A., Wan, Xiaohai, Garg, Sipi, Kowal, Karen, Cutler, Gordon B., Ross, Judith L.
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4154082/
https://ncbi.nlm.nih.gov/pubmed/24762109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2013-4518
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