Increased GDF9 and BMP15 mRNA levels in cumulus granulosa cells correlate with oocyte maturation, fertilization, and embryo quality in humans

BACKGROUND: Oocyte secreted factors (OSFs), including growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15), play an important role in the process of follicular development and oocyte maturation. Since OSFs are expressed in oocytes and cumulus granulosa cells, the aim of t...

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Autori principali: Li, Yi, Li, Rui-Qi, Ou, Song-Bang, Zhang, Ning-Feng, Ren, Ling, Wei, Li-Na, Zhang, Qing-Xue, Yang, Dong-Zi
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153897/
https://ncbi.nlm.nih.gov/pubmed/25139161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7827-12-81
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