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Enhancing Trial Integrity by Protecting the Independence of Data Monitoring Committees in Clinical Trials

BACKGROUND: Data Monitoring Committees (DMCs) have important roles in safeguarding patient interests and enhancing trial integrity and credibility. To effectively fulfill their responsibilities, DMCs should be independent of study sponsors, study investigators and caregivers managing study participa...

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Detalhes bibliográficos
Main Authors: Fleming, Thomas R., Hennekens, Charles H., Pfeffer, Marc A., DeMets, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153744/
https://ncbi.nlm.nih.gov/pubmed/24926941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/10543406.2014.925719
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