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Prominin-1 (CD133) Defines Both Stem and Non-Stem Cell Populations in CNS Development and Gliomas

Prominin-1 (CD133) is a commonly used cancer stem cell marker in central nervous system (CNS) tumors including glioblastoma (GBM). Expression of Prom1 in cancer is thought to parallel expression and function in normal stem cells. Using RNA in situ hybridization and antibody tools capable of detectin...

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Detalhes bibliográficos
Main Authors: Holmberg Olausson, Karl, Maire, Cecile L., Haidar, Sam, Ling, Jason, Learner, Emily, Nistér, Monica, Ligon, Keith L.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153667/
https://ncbi.nlm.nih.gov/pubmed/25184684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106694
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