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MALDI Imaging Mass Spectrometry Profiling of N-Glycans in Formalin-Fixed Paraffin Embedded Clinical Tissue Blocks and Tissue Microarrays

A recently developed matrix-assisted laser desorption/ionization imaging mass spectrometry (MALDI-IMS) method to spatially profile the location and distribution of multiple N-linked glycan species in frozen tissues has been extended and improved for the direct analysis of glycans in clinically deriv...

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Bibliographische Detailangaben
Hauptverfasser: Powers, Thomas W., Neely, Benjamin A., Shao, Yuan, Tang, Huiyuan, Troyer, Dean A., Mehta, Anand S., Haab, Brian B., Drake, Richard R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153616/
https://ncbi.nlm.nih.gov/pubmed/25184632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0106255
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