Treatment of Metastatic Extramammary Paget’s Disease Associated With Adnexal Adenocarcinoma, With Anti-HER2 Drugs Based on Genomic Alteration ERBB2 S310F

Extramammary Paget’s disease is a rare intraepithelial malignant condition affecting the apocrine gland-bearing skin. In this case, a genomic alteration, ERBB2 S310F mutation, was discovered. The ERBB2 S310F mutation seems to be a transforming mutation that should be targeted with anti-HER2 drugs. G...

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Bibliographic Details
Main Authors: Vornicova, Olga, Hershkovitz, Dov, Yablonski-Peretz, Tamar, Ben-Itzhak, Ofer, Keidar, Zohar, Bar-Sela, Gil
Format: Artigo
Language:Inglês
Published: AlphaMed Press 2014
Subjects:
Brief Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4153459/
https://ncbi.nlm.nih.gov/pubmed/25085898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2014-0054
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